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            Age-related loss of mobility and an increased risk of falling remain major obstacles for older adults to live independently. Many elderly people lack the coordination and strength necessary to perform activities of daily living, such as getting out of bed or stepping into a bathtub. A traditional solution is to install grab bars around the home. For assisting in bathtub transitions, grab bars are fixed to a bathroom wall. However, they are often too far to reach and stably support the user; the installation locations of grab bars are constrained by the room layout and are often suboptimal. In this paper, we present a mobile robot that provides an older adult with a handlebar located anywhere in space - “Handle Anywhere”. The robot consists of an omnidirectional mobile base attached to a repositionable handlebar. We further develop a methodology to optimally place the handle to provide the maximum support for the elderly user while performing common postural changes. A cost function with a trade-off between mechanical advantage and manipulability of the user’s arm was optimized in terms of the location of the handlebar relative to the user. The methodology requires only a sagittal plane video of the elderly user performing the postural change, and thus is rapid, scalable, and uniquely customizable to each user. A proof-of-concept prototype was built, and the optimization algorithm for handle location was validated experimentally.more » « less
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            Bonato, Paolo (Ed.)Over the past two decades Biomedical Engineering has emerged as a major discipline that bridges societal needs of human health care with the development of novel technologies. Every medical institution is now equipped at varying degrees of sophistication with the ability to monitor human health in both non-invasive and invasive modes. The multiple scales at which human physiology can be interrogated provide a profound perspective on health and disease. We are at the nexus of creating “avatars” (herein defined as an extension of “digital twins”) of human patho/physiology to serve as paradigms for interrogation and potential intervention. Motivated by the emergence of these new capabilities, the IEEE Engineering in Medicine and Biology Society, the Departments of Biomedical Engineering at Johns Hopkins University and Bioengineering at University of California at San Diego sponsored an interdisciplinary workshop to define the grand challenges that face biomedical engineering and the mechanisms to address these challenges. The Workshop identified five grand challenges with cross-cutting themes and provided a roadmap for new technologies, identified new training needs, and defined the types of interdisciplinary teams needed for addressing these challenges. The themes presented in this paper include: 1) accumedicine through creation of avatars of cells, tissues, organs and whole human; 2) development of smart and responsive devices for human function augmentation; 3) exocortical technologies to understand brain function and treat neuropathologies; 4) the development of approaches to harness the human immune system for health and wellness; and 5) new strategies to engineer genomes and cells.more » « less
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